Shedding
From UroWiki
Shedding is the process whereby lizards' skin peels off - it is similar to the moulting of feathers from birds, and generally falls off in pieces (unlike snakes, for example, which generally shed their entire skin all at once). This may look unsightly but is perfectly normal behaviour. Shed or partially-shed skin may remain attached to the lizard for some time, even for a number of months; you should never pull off a piece of shed which is still attached to your lizard, although it is fairly common for lizards to pull this off themselves, often eating the skin in the process. Shedding happens all year round.
Wild caught Uromastyx may have issues with shedding in small pieces. Do not worry if they shed little by little, as they have gone through the stress of being caught, shipped, crowded, kept in less then optimal conditions, etc. Allow them time to shed and after a few sheds you will notice their behavior changes and they will shed in larger sections. Healthy uromastyx and most captive bred uromastyx will shed large pieces over a period of time. You may also observe a uromastyx shed its legs more often then it sheds its tail. This is all natural to them and just be sure to allow them to shed on their own. There is no major need to assist them in shedding. Should there become several dried out damaged layers of skin you may want to consult a qualified herp vet, but even then NOBODY should ever pull on the skin of your Uromastyx.
During a shed you should keep an eye on your lizard's toes - sometimes they develop 'rings' of shed skin that can cut off circulation. If this occurs, it is one circumstance where you should intervene, but be very careful so as not to damage the feet or toes. If your uromastyx develops some problem spots that remain unshed after several shed cycles, rubbing a small amount of mineral oil on the affected area is one possible solution.
Tail shed and tail rot
Some owners have panicked at odd-looking or long-lasting shed on the tail, but this is not usually an indication of tail rot, unless the lizard has been recently immersed in water (not recommended).
